GLP-1 2mg Vial
What is GLP-1?
Glucagon-like Peptide 1 is a 30-amino acid peptide hormone produced in the intestinal epithelial endocrine L-cells by differential processing of proglucagon, the gene which is expressed in these cells. Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. Plays an important role in initiating and maintaining hyperglycemic conditions in diabetes.
GLP-1 is a proglucagon-derived peptide hormone secreted primarily by intestinal L cells during feeding. Its major physiological function is the stimulation of pancreatic β cells to release appropriate amounts of insulin after glucose absorption.
Biological actions exhibited by this product include the suppression of plasma glucagon levels, inhibition of gastric motility, and promotion of satiety. The secretion of Glucagon-like Peptide 1 from intestinal L cells is stimulated by nutrients, hormones, and neural inputs. On the other hand, insulin has been reported to inhibit GLP-1 release, indicating that a feedback loop mechanism regulates its secretion.
In clinical and research settings, this peptide augments insulin release in a glucose dependent manner. It is also useful in increasing beta cells mass and insulin gene expression. Perhaps it’s most obvious uses include it’s remarkable ability to increase gastric emptying in the stomach and decrease food intake.